A dual action small molecule enhances azoles and overcomes resistance through co-targeting Pdr5 and Vma1

Liu, NN; Zhou, J; Jiang, T; Tarsio, M; Yu, FF; Zheng, XH; Qi, WJ; Liu, L; Tan, JC; Wei, LQ; Ding, J; Li, JQ; Zeng, LB; Ren, B; Huang, XT; Peng, YB; Cao, YB; Zhao, YB; Zhang, XY; Kane, PM; Chen, CB; Wang, H

Liu, NN; Wang, H (通讯作者)，Shanghai Jiao Tong Univ, Ctr Single Cell Om, Sch Publ Hlth, State Key Lab Oncogenes & Related Genes,Sch Med, Shanghai, Peoples R China.;Chen, CB (通讯作者)，Chinese Acad Sci, Inst Pasteur Shanghai, Ctr Microbes Dev & Hlth, Key Lab Mol Virol & Immunol, Shanghai, Peoples R China.;Chen, CB (通讯作者)，Univ Chinese Acad Sci, Beijing, Peoples R China.

TRANSLATIONAL RESEARCH, 2022; 247 (): 39

Abstract

Fungal infection threatens human health worldwide due to the limited arsenal of antifungals and the rapid emergence of resistance. Epidermal growth fa......

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