Loss of legumain induces premature senescence and mediates aging-related renal fibrosis

Wang, DK; Kang, LC; Chen, C; Guo, JS; Du, LF; Zhou, DH; Li, G; Zhang, YY; Mi, X; Zhang, MZ; Liu, SX; Tan, XY

Tan, XY (通讯作者),Nankai Univ, Sch Med, Dept Pathol, Tianjin 300071, Peoples R China.

AGING CELL, 2022; 21 (3):

Abstract

Aging is an independent risk factor for acute kidney injury and subsequent chronic kidney diseases, while the underlying mechanism is still elusive. H......

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