In vitro and in vivo anti-metastatic effect of the alkaliod matrine from Sophora flavecens on hepatocellular carcinoma and its mechanisms

Dai, MQ; Chen, NN; Li, JZ; Tan, LZ; Li, XJ; Wen, JY; Lei, LS; Guo, D

Guo, D (corresponding author), Southern Med Univ, Dept Pharm, Nanfang Hosp, 1838,Guangzhou Blvd North, Guangzhou 510515, Peoples R China.; Guo, D (corresponding author), Southern Med Univ, Sch Pharmaceut Sci, Guangdong Prov Key Lab New Drug Screening, Guangzhou 510515, Peoples R China.

PHYTOMEDICINE, 2021; 87 ():

Abstract

Backgrounds: Hepatocellular carcinoma (HCC) is one of the most prevalent and lethal cancer with high metastasis and recurrence rates. Hypoxia-induced ......

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