Discovery and Development of the Oral Complement Factor D Inhibitor Danicopan (ACH-4471)

Wiles, JA; Galvan, MD; Podos, SD; Geffner, M; Huang, MJ

Huang, MJ (corresponding author), Achill Pharmaceut, Drug Discovery, New Haven, CT 06511 USA.

CURRENT MEDICINAL CHEMISTRY, 2020; 27 (25): 4165

Abstract

Complement plays a vital role in our innate immune defense against invasive microorganisms. Excessive complement activation or insufficient control of......

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