Functional and structural characteristics of HLA-B*13:01-mediated specific T cells reaction in dapsone-induced drug hypersensitivity

Jiang, HQ; Wang, CW; Wang, ZX; Dai, YF; Zhu, YP; Lee, YS; Cao, Y; Chung, WH; Ouyang, SY; Wang, HS

Wang, HS (通讯作者)，Chinese Acad Med Sci & Peking Union Med Coll, Inst Dermatol, Jiangsu Key Lab Mol Biol Skin Dis & STIs, Dept Mycobacterium, Nanjing, Peoples R China.;Wang, HS (通讯作者)，Chinese Acad Med Sci & Peking Union Med Coll, Hosp Skin Dis, Nanjing, Peoples R China.;Wang, HS (通讯作者)，Nanjing Med Univ, Ctr Global Hlth, Sch Publ Hlth, Nanjing, Peoples R China.;Chung, WH (通讯作者)，Chang Gung Mem Hosp, Canc Vaccine & Immune Cell Therapy Core Lab, Drug Hypersensit Clin & Res Ctr, Dept Dermatol, Taipei, L

JOURNAL OF BIOMEDICAL SCIENCE, 2022; 29 (1):

Abstract

Background: Severe cutaneous adverse drug reactions (SCARs) are a group of serious clinical conditions caused by immune reaction to certain drugs. The......

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