Machine learning predictions of MHC-II specificities reveal alternative binding mode of class II epitopes

Racle, J; Guillaume, P; Schmidt, J; Michaux, J; Larabi, A; Lau, K; Perez, MAS; Croce, G; Genolet, R; Coukos, G; Zoete, V; Pojer, F; Bassani-Sternberg, M; Harari, A; Gfeller, D

Racle, J; Gfeller, D (通讯作者),Univ Lausanne, Ludwig Inst Canc Res, Dept Oncol UNIL CHUV, Lausanne, Switzerland.;Racle, J; Gfeller, D (通讯作者),Swiss Inst Bioinformat SIB, Lausanne, Switzerland.;Racle, J; Gfeller, D (通讯作者),Agora Canc Res Ctr, Lausanne, Switzerland.;Racle, J; Gfeller, D (通讯作者),Swiss Canc Ctr Leman SCCL, Lausanne, Switzerland.

IMMUNITY, 2023; 56 (6): 1359

Abstract

CD4+T cells orchestrate the adaptive immune response against pathogens and cancer by recognizing epitopes presented on class II major histocompatibili......

Full Text Link