Replication Fork Activation Is Enabled by a Single-Stranded DNA Gate in CMG Helicase

Wasserman, MR; Schauer, GD; O'Donnell, ME; Liu, SX

Liu, SX (reprint author), Rockefeller Univ, Lab Nanoscale Biophys & Biochem, New York, NY 10065 USA.; O'Donnell, ME (reprint author), Rockefeller Univ, Lab DNA Replicat, New York, NY 10065 USA.; O'Donnell, ME (reprint author), Rockefeller Univ, Howard Hug

CELL, 2019; 178 (3): 600

Abstract

The eukaryotic replicative helicase CMG is a closed ring around double-stranded (ds) DNA at origins yet must transition to single-stranded (ss) DNA fo......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索