Recruiting RyRs to Open in a Ca2+ Release Unit: Single-RyR Gating Properties Make RyR Group Dynamics

Gillespie, D

Gillespie, D (corresponding author), Rush Univ, Dept Physiol & Biophys, Med Ctr, Chicago, IL 60612 USA.

BIOPHYSICAL JOURNAL, 2020; 118 (1): 232

Abstract

In cardiac myocytes, clusters of type-2 ryanodine receptors (RyR2s) release Ca2+ from the sarcoplasmic reticulum (SR) via a positive feedback mechanis......

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