Unveiling E2F4, TEAD1 and AP-1 as regulatory transcription factors of the replicative senescence program by multi-omics analysis

Wang, YT; Liu, LP; Song, YF; Yu, XJ; Deng, HK

Deng, HK (通讯作者)，Peking Univ, Sch Basic Med Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China.;Deng, HK (通讯作者)，Peking Univ, Coll Life Sci, Peking Tsinghua Ctr Life Sci, MOE Key Lab Cell Proliferat & Differentiat, Beijing 100871, Peoples R China.;Deng, HK (通讯作者)，Peking Univ, Sch Chem Biol & Biotechnol, State Key Lab Chem Oncogen, Shenzhen Grad Sch, Shenzhen 518055, Peoples R China.

PROTEIN & CELL, 2022; 13 (10): 742

Abstract

Senescence, a stable state of growth arrest, affects many physiological and pathophysiological processes, especially aging. Previous work has indicate......

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