Bivalent non-human gal-α1-3-gal glycan epitopes in the Fc region of a monoclonal antibody model can be recognized by anti-Gal-α1-3-Gal IgE antibodies

Hatfield, G; Tepliakova, L; Tran, J; Lu, HX; Gilbert, M; Tam, RY

Tam, RY (通讯作者)，Hlth Canada, Ctr Oncol Radiopharmaceut & Res, Biol & Radiopharmaceut Drugs Directorate, Ottawa, ON K1A 0K9, Canada.

MABS, 2023; 15 (1):

Abstract

Monoclonal antibody (mAb) production using non-human cells can introduce non-human glycan epitopes including terminal galactosyl-a1-3-galactose (a1-3-......

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