PTRF/Cavin-1 as a Novel RNA-Binding Protein Expedites the NF-kappa B/PD-L1 Axis by Stabilizing lncRNA NEAT1, Contributing to Tumorigenesis and Immune Evasion in Glioblastoma

Yi, KK; Cui, XT; Liu, X; Wang, YF; Zhao, JX; Yang, SX; Xu, C; Yang, ERY; Xiao, ML; Hong, B; Fang, C; Kang, CS; Tan, YL; Wang, QX

Wang, QX (通讯作者)，Tianjin Med Univ, Minist Educ, Key Lab Postneuro Injury Neurorepair & Regenerat, Gen Hosp,Lab Neurooncol,Tianjin Neurol Inst, Tianjin, Peoples R China.;Tan, YL (通讯作者)，Key Lab Precise Diag & Treatment Glioma Hebei Pro, Baoding, Peoples R China.;Tan, YL (通讯作者)，Hebei Univ, Affiliated Hosp, Dept Pathol, Baoding, Peoples R China.;Tan, YL (通讯作者)，Hebei Univ, Sch Basic Med Sci, Dept Pathol, Baoding, Peoples R China.

FRONTIERS IN IMMUNOLOGY, 2022; 12 ():

Abstract

BackgroundImmunotherapy, especially checkpoint inhibitors targeting PD-1 or PD-L1, has revolutionized cancer therapy. However, PD-1/PD-L1 inhibitors h......

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