A 3D microfluidic liver model for high throughput compound toxicity screening in the OrganoPlate (R)

Bircsak, KM; DeBiasio, R; Miedel, M; Alsebahi, A; Reddinger, R; Saleh, A; Shun, TY; Vernetti, LA; Gough, A

Bircsak, KM (corresponding author), Mimetas Us Inc, Gaithersburg, MD 20878 USA.; Gough, A (corresponding author), Univ Pittsburgh, Drug Discovery Inst, Pittsburgh, PA 15260 USA.; Gough, A (corresponding author), Univ Pittsburgh, Dept Computat & Syst Biol, Pittsburgh, PA 15260 USA.

TOXICOLOGY, 2021; 450 ():

Abstract

We report the development, automation and validation of a 3D, microfluidic liver-on-a-chip for high throughput hepatotoxicity screening, the OrganoPla......

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