Compression of morbidity in a progeroid mouse model through the attenuation of myostatin/activin signalling

Alyodawi, K; Vermeij, WP; Omairi, S; Kretz, O; Hopkinson, M; Solagna, F; Joch, B; Brandt, RMC; Barnhoorn, S; van Vliet, N; Ridwan, Y; Essers, J; Mitchell, R; Morash, T; Pasternack, A; Ritvos, O; Matsakas, A; Collins-Hooper, H; Huber, TB; Hoeijmakers,

Patel, K (reprint author), Univ Reading, Sch Biol Sci, Reading, Berks, England.; Patel, K (reprint author), Freiburg Inst Adv Studies, Freiburg, Germany.; Patel, K (reprint author), Ctr Biol Syst Anal, Freiburg, Germany.

JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2019; 10 (3): 662

Abstract

Background One of the principles underpinning our understanding of ageing is that DNA damage induces a stress response that shifts cellular resources ......

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