MLL2 conveys transcription-independent H3K4 trimethylation in oocytes

Hanna, CW; Taudt, A; Huang, JH; Gahurova, L; Kranz, A; Andrews, S; Dean, W; Stewart, AF; Colome-Tatche, M; Kelsey, G

Kelsey, G (reprint author), Babraham Inst, Epigenet Programme, Cambridge, England.; Kelsey, G (reprint author), Univ Cambridge, Ctr Trophoblast Res, Cambridge, England.; Stewart, AF (reprint author), Tech Univ Dresden, Biotechnol Ctr, Tatzberg, Germany.

NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2018; 25 (1): 73

Abstract

Histone 3 K4 trimethylation (depositing H3K4me3 marks) is typically associated with active promoters yet paradoxically occurs at untranscribed domains......

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