Upf proteins: highly conserved factors involved in nonsense mRNA mediated decay

Gupta, P; Li, YR

Li, YR (reprint author), Harvard Univ, Harvard Med Sch, Boston, MA 02115 USA.; Li, YR (reprint author), Zhejiang Univ, Coll Life Sci, 866 Yu Hang Tang Rd, Hangzhou 310058, Zhejiang, Peoples R China.

MOLECULAR BIOLOGY REPORTS, 2018; 45 (1): 39

Abstract

Over 10% of genetic diseases are caused by mutations that introduce a premature termination codon in protein-coding mRNA. Nonsense-mediated mRNA decay......

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