Structure of the human ATM kinase and mechanism of Nbs1 binding

Warren, C; Pavletich, NP

Pavletich, NP (通讯作者)，Mem Sloan Kettering Canc Ctr, Struct Biol Program, 1275 York Ave, New York, NY 10021 USA.;Pavletich, NP (通讯作者)，Mem Sloan Kettering Canc Ctr, Howard Hughes Med Inst, New York, NY 10021 USA.

ELIFE, 2022; 11 ():

Abstract

DNA double-strand breaks (DSBs) can lead to mutations, chromosomal rearrangements, genome instability, and cancer. Central to the sensing of DSBs is t......

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