Addicted to proteostasis: How KRAS-driven cancers acquire resistance to clinical KRAS inhibitors

Klein, AT; Mendillo, ML

Mendillo, ML (通讯作者)，Northwestern Univ, Feinberg Sch Med, Dept Biochem & Mol Genet, Chicago, IL 60611 USA.;Mendillo, ML (通讯作者)，Northwestern Univ, Simpson Querrey Ctr Epigenet, Feinberg Sch Med, Chicago, IL 60611 USA.;Mendillo, ML (通讯作者)，Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Feinberg Sch Med, Chicago, IL 60611 USA.

CELL CHEMICAL BIOLOGY, 2023; 30 (11): 1334

Abstract

The development of KRAS inhibitors was a remarkable feat, yet their efficacy is limited by inevitable resis-tance. In the September issue of Science, ......

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