Suppression of AMPK/aak-2 by NRF2/SKN-1 down-regulates autophagy during prolonged oxidative stress

Kosztelnik, M; Kurucz, A; Papp, D; Jones, E; Sigmond, T; Barna, J; Traka, MH; Lorincz, T; Szarka, A; Banhegyi, G; Vellai, T; Korcsmaros, T; Kapuy, O

Korcsmaros, T (reprint author), Earlham Inst, Norwich Res Pk, Norwich NR4 7UZ, Norfolk, England.; Kapuy, O (reprint author), Semmelweis Univ, Dept Med Chem Mol Biol & Pathobiochem, Tuzolto Utca 37-47, H-1094 Budapest, Hungary.

FASEB JOURNAL, 2019; 33 (2): 2372

Abstract

NF-E2-related factor 2 (NRF2) transcription factor has a fundamental role in cell homeostasis maintenance as one of the master regulators of oxidative......

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