Stereocontrolled total synthesis of Resolvin D4 and 17(R)-Resolvin D4

Nshimiyimana, R; Glynn, SJ; Serhan, CN; Petasis, NA

Nshimiyimana, R; Petasis, NA (通讯作者),Univ Southern Calif, Dept Chem, Los Angeles, CA 90089 USA.;Nshimiyimana, R; Petasis, NA (通讯作者),Univ Southern Calif, Loker Hydrocarbon Res Inst, Los Angeles, CA 90089 USA.;Nshimiyimana, R (通讯作者),Brigham & Womens Hosp, Ctr Expt Therapeut & Reperfus Injury, Dept Anesthesiol, Boston, MA 02115 USA.;Nshimiyimana, R (通讯作者),Harvard Med Sch, Boston, MA 02115 USA.

ORGANIC & BIOMOLECULAR CHEMISTRY, 2023; 21 (8): 1666

Abstract

The total synthesis of Resolvin D4 and its 17(R)-hydroxy-epimer is reported. These lipid-based natural products are biosynthesized from docosahexaenoi......

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