Cancer-associated SF3B1 mutants recognize otherwise inaccessible cryptic 3 ' splice sites within RNA secondary structures

Kesarwani, AK; Ramirez, O; Gupta, AK; Yang, X; Murthy, T; Minella, AC; Pillai, MM

Pillai, MM (reprint author), Yale Canc Ctr, Sect Hematol, 300 George St, New Haven, CT 06511 USA.; Pillai, MM (reprint author), Yale Univ, Sch Med, 300 George St, New Haven, CT 06511 USA.

ONCOGENE, 2017; 36 (8): 1123

Abstract

Recurrent mutations in core splicing factors have been reported in several clonal disorders, including cancers. Mutations in SF3B1, a component of the......

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