SIRT1 Protects Dopaminergic Neurons in Parkinson's Disease Models via PGC-1 alpha-Mediated Mitochondrial Biogenesis

Chen, Y; Jiang, YH; Yang, YN; Huang, XZ; Sun, C

Sun, C (corresponding author), Nantong Univ, Key Lab Neuroregenerat Jiangsu, 19 Qixiu Rd, Nantong, Peoples R China.; Sun, C (corresponding author), Nantong Univ, Minist Educ, NMPA Key Lab Res & Evaluat Tissue Engn Technol Pr, 19 Qixiu Rd, Nantong, Peoples R China.; Sun, C (corresponding author), Nantong Univ, Inst Translat Med Cardiothorac Dis, Nantong Key Lab Translat Med Cardiothorac Dis, Affiliated Hosp, 20 Xishi Rd, Nantong, Peoples R China.

NEUROTOXICITY RESEARCH, 2021; 39 (5): 1393

Abstract

SIRT1 is a deacetylase with multiple physiological functions by targeting histones and non-histone proteins. It has been shown that SIRT1 activation i......

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