In-Vivo Degradation of DNA-Based Therapeutic BC 007 in Humans

Davideit, H; Becker, S; Muller, J; Becker, NP; Gottel, P; Abay, A; Sinn, A; Grossmann, M; Mallek, M; Haberland, A; Weisshoff, H

Haberland, A (reprint author), Berlin Cures GmbH, Robert Rossle Str 10, D-13125 Berlin, Germany.

EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, 2019; 44 (4): 567

Abstract

Background and ObjectivesSince there is no clear evidence in the literature to show how non-modified single-stranded DNA (ssDNA) drugs are metabolized......

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