Macrophage dysfunction initiates colitis during weaning of infant mice lacking the interleukin-10 receptor

Redhu, NS; Bakthavatchalu, V; Conway, EA; Shouval, DS; Tsou, A; Goettel, JA; Biswas, A; Wang, CW; Field, M; Muller, W; Bleich, A; Li, N; Gerber, GK; Bry, L; Fox, JG; Snapper, SB; Horwitz, BH

Snapper, SB (reprint author), Boston Childrens Hosp, Div Gastroenterol Hepatol & Nutr, Boston, MA 02115 USA.; Snapper, SB; Horwitz, BH (reprint author), Harvard Med Sch, Boston, MA 02115 USA.; Horwitz, BH (reprint author), Brigham & Womens Hosp, Dept Path

ELIFE, 2017; 6 ( ):

Abstract

Infants with defects in the interleukin 10 receptor (IL10R) develop very early onset inflammatory bowel disease. Whether IL10R regulates lamina propri......

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