Small Molecule Microarray Based Discovery of PARP14 Inhibitors

Peng, B; Thorsell, AG; Karlberg, T; Schuler, H; Yao, SQ

Yao, SQ (reprint author), Natl Univ Singapore, Dept Chem, 3 Sci Dr, Singapore 117543, Singapore.; Schuler, H (reprint author), Karolinska Inst, Dept Med Biochem & Biophys, Scheeles Vag 2, S-17177 Stockholm, Sweden.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2017; 56 (1): 248

Abstract

Poly(ADP-ribose) polymerases (PARPs) are key enzymes in a variety of cellular processes. Most small-molecule PARP inhibitors developed to date have be......

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