Hypomethylation of STAT1 and HLA-DRB1 is associated with type-I interferon-dependent HLA-DRB1 expression in lupus CD8+T cells

Miller, S; Tsou, PS; Coit, P; Gensterblum-Miller, E; Renauer, P; Rohraff, DM; Kilian, NC; Schonfeld, M; Sawalha, AH

Sawalha, AH (reprint author), Univ Michigan, Dept Internal Med, Div Rheumatol, Ann Arbor, MI 48109 USA.

ANNALS OF THE RHEUMATIC DISEASES, 2019; 78 (4): 519

Abstract

Objective We examined genome-wide DNA methylation changes in CD8+ T cells from patients with lupus and controls and investigated the functional releva......

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