CCR8 marks highly suppressive Treg cells within tumours but is dispensable for their accumulation and suppressive function

Whiteside, SK; Grant, FM; Gyori, DS; Conti, AG; Imianowski, CJ; Kuo, P; Nasrallah, R; Sadiyah, F; Lira, SA; Tacke, F; Eil, RL; Burton, OT; Dooley, J; Liston, A; Okkenhaug, K; Yang, J; Roychoudhuri, R

Whiteside, SK; Roychoudhuri, R (corresponding author), Univ Cambridge, Dept Pathol, Tennis Court Rd, Cambridge CB2 1QP, England.

IMMUNOLOGY, 2021; 163 (4): 512

Abstract

CD4(+) regulatory T (Treg) cells, dependent upon the transcription factor Foxp3, contribute to tumour immunosuppression but are also required for immu......

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