Sirtuin 6 (SIRT6) regulates redox homeostasis and signaling events in human articular chondrocytes

Collins, JA; Kapustina, M; Bolduc, JA; Pike, JFW; Diekman, BO; Mix, K; Chubinskaya, S; Eroglu, E; Michel, T; Poole, LB; Furdui, CM; Loeser, RF

Loeser, RF (corresponding author), Univ N Carolina, Thurston Arthrit Res Ctr, 3300 Thurston Bldg,Campus Box 7280, Chapel Hill, NC 27517 USA.; Collins, JA (corresponding author), Thomas Jefferson Univ, Dept Orthopaed Surg, Sidney Kimmel Med Coll, 1015 Walnut St, Philadelphia, PA 19107 USA.

FREE RADICAL BIOLOGY AND MEDICINE, 2021; 166 (): 90

Abstract

The nuclear localized protein deacetylase, SIRT6, has been identified as a crucial regulator of biological processes that drive aging. Among these pro......

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