The IFN-lambda-IFN-lambda R1-IL-10R beta Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity

Mendoza, JL; Schneider, WM; Hoffmann, HH; Vercauteren, K; Jude, KM; Xiong, AM; Moraga, I; Horton, TM; Glenn, JS; de Jong, YP; Rice, CM; Garcia, KC

Garcia, KC (reprint author), Stanford Univ, Sch Med, Howard Hughes Med Inst, Dept Mol & Cellular Physiol, Stanford, CA 94305 USA.; Garcia, KC (reprint author), Stanford Univ, Sch Med, Dept Biol Struct, Stanford, CA 94305 USA.

IMMUNITY, 2017; 46 (3): 379

Abstract

Type III interferons (IFN-lambda s) signal through a heterodimeric receptor complex composed of the IFN-lambda R1 subunit, specific for IFN-lambda s, ......

Full Text Link