ALK2 Receptor Kinase Association with FKBP12.6 Is Structurally Conserved with the ALK2-FKBP12 Complex

Williams, E; Riesebos, E; Kerr, G; Bullock, AN

Bullock, AN (corresponding author), Univ Oxford, Ctr Med Discovery, Old Rd Campus Res Bldg,Roosevelt Dr, Oxford OX3 7DQ, England.

BIOMEDICINES, 2021; 9 (2):

Abstract

The immunophilin FKBP12 is a known inhibitor of type I BMP and TGF-beta receptors that competes for binding with their substrate SMADs. FKBP12 and the......

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