Quality by design applied to olanzapine and quetiapine LC-MS/MS bioanalysis

Branco, DDC; Bedor, NCTC; Silva, CS; Bedor, DCG; Pimentel, MF; de Santana, DP

Bedor, DCG (corresponding author), Univ Fed Pernambuco, Pharmaceut & Cosmet Dev Ctr NUDFAC, Ave Prof Artur Sa S-N,Cidade Univ, BR-50730420 Recife, PE, Brazil.; Bedor, DCG (corresponding author), B&S Innovat Dev & Anal Pharmaceut Prod, Rua Costa Sepulveda 749, BR-50730260 Recife, PE, Brazil.

JOURNAL OF CHROMATOGRAPHIC SCIENCE, 2020; 58 (2): 117

Abstract

One major challenge in quantifying drugs in biological matrices is to manage interfering compounds. A technique such liquid chromatography coupled to ......

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