Immunization with a Synthetic Human MUC1 Glycopeptide Vaccine against Tumor-Associated MUC1 Breaks Tolerance in Human MUC1 Transgenic Mice

Stergiou, N; Glaffig, M; Jonuleit, H; Schmitt, E; Kunz, H

Schmitt, E (reprint author), Johannes Gutenberg Univ Mainz, Univ Med Ctr, Inst Immunol, Langenbeckstr 1,Bldg 708, Mainz, Germany.; Kunz, H (reprint author), Johannes Gutenberg Univ Mainz, Inst Organ Chem, Duesbergweg 10-14, D-55128 Mainz, Germany.

CHEMMEDCHEM, 2017; 12 (17): 1424

Abstract

Breaking tolerance is crucial for effective tumor immunotherapy. We showed that vaccines containing tumor-associated human MUC1 glycopeptides induce s......

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