Preferential expansion of CD8+CD19-CAR T cells postinfusion and the role of disease burden on outcome in pediatric B-ALL

Talleur, AC; Qudeimat, A; Metais, JY; Langfitt, D; Mamcarz, E; Crawford, JC; Huang, SJ; Cheng, C; Hurley, C; Madden, R; Sharma, A; Suliman, A; Srinivasan, A; Velasquez, MP; Obeng, EA; Willis, C; Akel, S; Karol, SE; Inaba, H; Bragg, A; Zheng, WT; Zhou, SM; Schell, S; Tuggle-Brown, M; Cullins, D; Patil, SL; Li, Y; Thomas, PG; Zebley, C; Youngblood, B; Pui, CH; Lockey, T; Geiger, TL; Meagher, MM; Triplett, BM; Gottschalk, S

Talleur, AC (通讯作者),St Jude Childrens Res Hosp, Dept Bone Marrow Transplantat & Cellular Therapy, 262 Danny Thomas Pl,MS1130, Memphis, TN 38105 USA.;Gottschalk, S (通讯作者),St Jude Childrens Res Hosp, Dept Bone Marrow Transplantat & Cellular Therapy, 262 Danny Thomas Pl,MS321, Memphis, TN 38105 USA.

BLOOD ADVANCES, 2022; 6 (21): 5737

Abstract

T cells expressing CD19-specific chimeric antigen receptors (CD19-CARs) have potent antileukemia activity in pediatric and adult patients with relapse......

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