Synthesis of 8-Substituted 2-Deoxyisoguanosines via Unprotected 8-Brominated 2-Amino-2-deoxyadenosine

Zhang, W; Gao, Q; Wei, SX; Fu, BC; Yang, Q; Ming, X

Ming, X (reprint author), Chengdu Med Coll, Dept Pharm, 783 Xindu Ave, Chengdu 610500, Sichuan, Peoples R China.; Ming, X (reprint author), Study Struct Specif Small Mol Drug Sichuan Prov C, 783 Xindu Ave, Chengdu 610500, Sichuan, Peoples R China.

CHEMISTRY & BIODIVERSITY, 2018; 15 (1):

Abstract

A variety of applications of 8-alkynylated nucleosides has prompted the synthesis of new purine analogues. Bromination of unprotected 2-amino-2-deoxya......

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