Local Ca2+ signals couple activation of TRPV1 and ANO1 sensory ion channels

Shah, S; Carver, CM; Mullen, P; Milne, S; Lukacs, V; Shapiro, MS; Gamper, N

Gamper, N (corresponding author), Univ Leeds, Fac Biol Sci, Sch Biomed Sci, Leeds LS2 9JT, W Yorkshire, England.; Gamper, N (corresponding author), Hebei Med Univ, Dept Pharmacol, Shijiazhuang 050017, Hebei, Peoples R China.

SCIENCE SIGNALING, 2020; 13 (629):

Abstract

ANO1 (TMEM16A) is a Ca2+-activated Cl- channel (CaCC) expressed in peripheral somatosensory neurons that are activated by painful (noxious) stimuli. T......

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