Research Progress on Small-molecule Inhibitors of Protein Arginine Methyltransferase 5 (PRMT5) for Treating Cancer

Guo, CH; Wu, LT; Zheng, XM; Zhao, L; Hou, XJ; Wang, ZJ; Han, C

Wang, ZJ; Han, C (通讯作者),Changzhi Univ, Dept Chem, Key Lab Antitumor Drugs & Compan Diagnost Reagents, Changzhi 046011, Shanxi, Peoples R China.

CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2023; 23 (21): 2048

Abstract

Background: The protein arginine methyltransferase family includes nine members, with PRMT5 being the major type II arginine methyltransferase. PRMT5 ......

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