Simultaneous quantification of dabrafenib, hydroxy-dabrafenib and trametinib in human plasma by liquid chromatography-tandem mass spectrometry

Balakirouchenane, D; Khoudour, N; Guegan, S; Kramkimel, N; Franck, N; Rodier, T; Goldwasser, F; Dupin, N; Aractingi, S; Vidal, M; Blanchet, B

Balakirouchenane, D (corresponding author), Cochin Hosp, AP HP, CARPEM, Dept Pharmacokinet & Pharmacochem, F-75014 Paris, France.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021; 193 ():

Abstract

A new liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the simultaneous quantification of dabrafenib (DAB), its main metabolite hy......

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