Polycomb protein RING1A limits hematopoietic differentiation in myelodysplastic syndromes

Palau, A; Garz, AK; Diesch, J; Zwick, A; Malinverni, R; Valero, V; Lappin, K; Casquero, R; Lennartsson, A; Zuber, J; Navarro, T; Mills, KI; Gotze, KS; Buschbeck, M

Buschbeck, M (reprint author), Univ Autonoma Barcelona, Josep Carreras Leukaemia Res Inst, Campus ICO Germans Trias & Pujol, Badalona, Spain.; Buschbeck, M (reprint author), Germans Trias & Pujol Res Inst PMPPC IGTP, Program Predict & Personalized Med Can

ONCOTARGET, 2017; 8 (70): 115002

Abstract

Genetic lesions affecting epigenetic regulators are frequent in myelodysplastic syndromes (MDS). Polycomb proteins are key epigenetic regulators of di......

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