Discovery of AMG 510, a first-in-human covalent inhibitor of KRAS(G12C) for the treatment of solid tumors

Lanman, BA; Chen, JJ; Liu, LB; Lopez, P; Pickrell, AJ; Reed, AB; Wang, HL; Achanta, P; Canon, J; Erlanson, DA; Fucini, RV; Jeong, JW; Mohr, C; Saiki, AY; Cee, VJ; Lipford, JR; Rex, K; Volak, LP

CANCER RESEARCH, 2019; 79 (13):