ABT-737 potentiates cisplatin- induced apoptosis in human osteosarcoma cells via the mitochondrial apoptotic pathway

Zhang, FT; Yu, XL; Liu, XQ; Zhou, TH; Nie, T; Cheng, M; Liu, HC; Dai, M; Zhang, B

Dai, M; Zhang, B (reprint author), Nanchang Univ, Dept Orthoped, Artificial Joints Engn & Technol Res Ctr Jiangxi, Affiliated Hosp 1, 17 Yong Wai Zheng St, Nanchang 330006, Jiangxi, Peoples R China.

ONCOLOGY REPORTS, 2017; 38 (4): 2301

Abstract

ABT-737 is a BH-3 mimetic that inhibits Bcl-2 and induces apoptosis of cancer cells, which has potential for anticancer therapies. Studies have shown ......

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