Met inhibition revokes IFN gamma-induction of PD-1 ligands in MET-amplified tumours

Martin, V; Chiriaco, C; Modica, C; Acquadro, A; Cortese, M; Galimi, F; Perera, T; Gammaitoni, L; Aglietta, M; Comoglio, PM; Vigna, E; Sangiolo, D

Vigna, E (reprint author), IRCCS, FPO, Candiolo Canc Inst, Lab Gene Transfer, Turin, Italy.; Vigna, E (reprint author), Univ Torino, Dept Oncol, Turin, Italy.

BRITISH JOURNAL OF CANCER, 2019; 120 (5): 527

Abstract

BACKGROUND: Interferon-induced expression of programmed cell death ligands (PD-L1/PD-L2) may sustain tumour immuneevasion. Patients featuring MET ampl......

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