Circulating tumour DNA sequencing to determine therapeutic response and identify tumour heterogeneity in patients with paediatric solid tumours

Stankunaite, R; George, SL; Gallagher, L; Jamal, S; Shaikh, R; Yuan, LA; Hughes, D; Proszek, PZ; Carter, P; Pietka, G; Heide, T; James, C; Tari, H; Lynn, C; Jain, N; Portela, LR; Rogers, T; Vaidya, SJ; Chisholm, JC; Carceller, F; Szychot, E; Mandeville, H; Angelini, P; Jesudason, AB; Jackson, M; Marshall, LV; Gatz, SA; Anderson, J; Sottoriva, A; Chesler, L; Hubank, M

Chesler, L (通讯作者),Inst Canc Res, Div Clin Studies, Paediat Tumour Biol, London, England.;Hubank, M (通讯作者),Royal Marsden NHS Fdn, Inst Canc Res, Mol Pathol Sect, Clin Genom, London, England.

EUROPEAN JOURNAL OF CANCER, 2022; 162 (): 209

Abstract

Objective: Clinical diagnostic sequencing of circulating tumour DNA (ctDNA) is well advanced for adult patients, but application to paediatric cancer ......

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