Drug Discovery of Acetophenone Derivatives as BRD4 Inhibitors

Zhang, ZM; Huang, WH; Zheng, XL; Li, CS; Shen, ZR

Shen, ZR (corresponding author), Zhejiang Acad Med Sci, Inst Mat Med, Key Lab Neuropsychiat Drug Res Zhejiang Prov, Hangzhou 310013, Peoples R China.

LETTERS IN DRUG DESIGN & DISCOVERY, 2020; 17 (3): 323

Abstract

UBackground: The bromodomain and extra-terminal proteins (BET), in particular BRD4, has recently emerged as a potential therapeutic target for the tre......

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