Expression of PFKFB3 and Ki67 in lung adenocarcinomas and targeting PFKFB3 as a therapeutic strategy

Li, XL; Liu, J; Qian, L; Ke, HG; Yao, C; Tian, W; Liu, YF; Zhang, JG

Liu, YF; Zhang, JG (reprint author), Nantong Univ, Dept Pathol, Affiliated Hosp, 20 Xisi Rd, Nantong 226001, Jiangsu, Peoples R China.

MOLECULAR AND CELLULAR BIOCHEMISTRY, 2018; 445 (1-2): 123

Abstract

Phosphofructokinase-2/fructose-2, 6-bisphosphatase 3 (PFKFB3) catalyzes the synthesis of F2,6BP, which is an allosteric activator of 6-phosphofructo-1......

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