Development of NanoBRET-Binding Assays for FKBP-Ligand Profiling in Living Cells

Gnatzy, MT; Geiger, TM; Kuehn, A; Gutfreund, N; Walz, M; Kolos, JM; Hausch, F

Hausch, F (corresponding author), Tech Univ Darmstadt, Dept Chem & Biochem, Clemens Schopf Inst, Alarich Weiss Str 4, D-64287 Darmstadt, Germany.

CHEMBIOCHEM, 2021; 22 (13): 2257

Abstract

FK506-binding proteins (FKBPs) are promising targets for a variety of disorders and infectious diseases. High FKBP occupancy is thought to be necessar......

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