Gut microbiome determines therapeutic effects of OCA on NAFLD by modulating bile acid metabolism

Liu, JJ; Sun, JY; Yu, JK; Chen, H; Zhang, D; Zhang, T; Ma, YC; Zou, CG; Zhang, ZG; Ma, LQ; Yu, X

Yu, JK; Zhang, ZG (通讯作者)，Yunnan Univ, Sch Life Sci, State Key Lab Conservat & Utilizat Bioresources Yu, Kunming 650091, Yunnan, Peoples R China.;Yu, X (通讯作者)，Chinese Acad Med Sci & Peking Union Med Coll, Beijing Hosp, Inst Geriatr Med, Natl Ctr Gerontol, Beijing 100730, Peoples R China.;Ma, LQ (通讯作者)，Kunming Med Univ, Affiliated Hosp 1, Yunnan Inst Digest Dis, Yunnan Clin Res Ctr Digest Dis, Kunming 650032, Yunnan, Peoples R China.

NPJ BIOFILMS AND MICROBIOMES, 2023; 9 (1):

Abstract

Non-alcoholic fatty liver disease (NAFLD), the most common chronic liver disease, had no approved pharmacological agents yet. Obeticholic acid (OCA), ......

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