Enhancement of TKI sensitivity in lung adenocarcinoma through m6A-dependent translational repression of Wnt signaling by circ-FBXW7

Li, K; Peng, ZY; Wang, R; Li, X; Du, N; Liu, DP; Zhang, J; Zhang, YF; Ma, L; Sun, Y; Tang, SC; Ren, H; Yang, YP; Sun, X

Sun, X (通讯作者)，Xi An Jiao Tong Univ, Canc Ctr, Dept Thorac Surg, Dept Thorac Surg & Oncol,Affiliated Hosp 1, Xian 710061, Shaanxi, Peoples R China.;Sun, X (通讯作者)，Thomas Jefferson Univ, Sidney Kimmel Canc Ctr, Dept Pathol Anat & Cell Biol, Philadelphia, PA 19107 USA.

MOLECULAR CANCER, 2023; 22 (1):

Abstract

BackgroundTyrosine kinase inhibitors (TKIs) that specifically target mutational points in the EGFR gene have significantly reduced suffering and provi......

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