Adnectin-drug conjugates for Glypican-3-specific delivery of a cytotoxic payload to tumors

Lipovsek, D; Carvajal, I; Allentoff, AJ; Barros, A; Brailsford, J; Cong, Q; Cotter, P; Gangwar, S; Hollander, C; Lafont, V; Lau, WL; Li, WY; Moreta, M; O'Neil, S; Pinckney, J; Smith, MJ; Su, JL; Terragni, C; Wallace, MA; Wang, LF; Wright, M; Marsh, H

Lipovsek, D (reprint author), Bristol Myers Squibb Co, Mol Discovery Technol, Waltham, MA 02453 USA.

PROTEIN ENGINEERING DESIGN & SELECTION, 2018; 31 (5): 159

Abstract

Tumor-specific delivery of cytotoxic agents remains a challenge in cancer therapy. Antibody-drug conjugates (ADC) deliver their payloads to tumor cell......

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