A CRISPRi mediated self-inducible system for dynamic regulation of TCA cycle and improvement of itaconic acid production in Escherichia coli

Zhao, M; Li, YT; Wang, FQ; Ren, YH; Wei, DZ

Wang, FQ; Ren, YH (通讯作者),East China Univ Sci & Technol, Newworld Inst Biotechnol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China.

SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, 2022; 7 (3): 982

Abstract

Itaconic acid (ITA), an effective alternative fossil fuel, derives from the bypass pathway of the tricarboxylic acid (TCA) cycle. Therefore, the imbal......

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