FGFR-mediated ERK1/2 signaling contributes to mesendoderm and definitive endoderm formation in vitro

Lau, HH; Amirruddin, NS; Loo, LSW; Chan, JW; Iich, E; Krishnan, VG; Hoon, S; Keong, AK

Keong, AK (通讯作者)，ASTAR, Inst Mol & Cell Biol IMCB, Stem Cells & Diabet Lab, Proteos, Singapore, Singapore.;Keong, AK (通讯作者)，Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Med, Singapore, Singapore.;Keong, AK (通讯作者)，Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Biochem, Singapore, Singapore.;Keong, AK (通讯作者)，Natl Univ Singapore, Yong Loo Lin Sch Med, Precis Med Translat Res Programme, Singapore, Singapore.

ISCIENCE, 2023; 26 (8):

Abstract

The differentiation of human pluripotent stem cells into the SOX17(+) definitive endoderm (DE) germ layer is important for generating tissues for rege......

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