APRIL signaling via TACI mediates immunosuppression by T regulatory cells in multiple myeloma: therapeutic implications

Tai, YT; Lin, L; Xing, LJ; Cho, SF; Yu, TT; Acharya, C; Wen, K; Hsieh, PA; Dulos, J; van Elsas, A; Munshi, N; Richardson, P; Anderson, KC

Tai, YT; Anderson, KC (reprint author), Harvard Med Sch, Dana Farber Canc Inst, LeBow Inst Myeloma Therapeut, Jerome Lipper Multiple Myeloma Ctr, Boston, MA 02115 USA.

LEUKEMIA, 2019; 33 (2): 426

Abstract

We investigate here how APRIL impacts immune regulatory T cells and directly contributes to the immunosuppressive multiple myeloma (MM) bone marrow (B......

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